HOME CARE GUIDE How to Change a PICC Dressing: Step by Step Guide My partner has had a picc line fitted on 30th and it's still hurting lots and bleeding today.he's had two fitted with no luck (same issues) and this is the third one. PICC Line Care: Dressing Changes, Flushes, & More Care+Wear Central Line Dressing Change, , Central lines are at a high risk of serious infection. Proper central line care is a key to preventing these central line associated bloodstream infections called