Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 COM Jan. 2008 Diagnosis UW School of Dentistry Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Pigmented skin lesions The BMJ